Birc6 protein folding

Author: lesr

August undefined, 2024

WebA lentivirus-mediated silencing method was used to knockdown BIRC6, and the biological con-sequences of BIRC6 silencing in three hepatoma cell lines were investigated in vitro and in vivo. We found that BIRC6 overexpres-sion was significantly correlated with serum ALT level and HCC vascular invasion. Patients with positive BIRC6 expression in tumor WebThis gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein …

Expression of BIRC6 in cancer - Summary - The Human …

WebOriginal Article Overexpression of BIRC6 driven by EGF-JNK-HECTD1 signaling is a potential therapeutic target for triple-negative breast cancer Yongpeng Li,1 ,2 10Yanan Tan,34 Lijuan Wen,5 Zhihao Xing,6 Changxu Wang,7 Liuhui Zhang,8 Kai Wu,1 Haiyan Sun, 1Yuqing Li, Qifang Lei,1 and Song Wu ,9 1The Third Afﬁliated Hospital of Shenzhen … WebFeb 10, 2024 · Abstract. Background: Baculoviral IAP repeat containing 6 (BIRC6), a member of the inhibitors of apoptosis protein (IAP) family, has been reported to be correlated with oncogenesis. The aim of this study was to investigate the prognostic significance of BIRC6 in prostate cancer, as well as its effects on prostate cancer cell lines. list of healthcare software

Subcellular - BIRC6 - The Human Protein Atlas

WebBIRC6 (BRUCE) protein expression summary. Human assay: MCF-7 fixed with PFA, dilution: 1:200 Human assay: SH-SY5Y fixed with PFA, dilution: 1:200 This gene encodes a protein with a BIR (baculoviral inhibition of apoptosis protein repeat) domain and a UBCc (ubiquitin-conjugating enzyme E2, catalytic) domain. This protein inhibits apoptosis by facilitating the degradation of apoptotic proteins by ubiquitination. WebBIRC6 (BRUCE) protein expression summary. Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein li gase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 … iman\u0027s engagement ring from david bowie

Structural basis for regulation of apoptosis and …

Brain tissue expression of BIRC6 - Summary - Protein Atlas

WebWhether it's raining, snowing, sleeting, or hailing, our live precipitation map can help you prepare and stay dry. WebFeb 9, 2024 · The enormous protein BIRC6 plays an important role in preventing programmed cell death – earning BIRC6 the nickname "Guardian of the Cell". Scientists from the lab of Tim Clausen now showed that BIRC6’s structure holds the key for regulating cell death, but also for cell survival pathways. Their findings are published in the journal … iman\u0027s father mohamed abdulmajidWebNational Center for Biotechnology Information list of healthcare stock

"WebBIRC6 is part of cluster 45 Non-specific - Cell proliferation with confidence i ... RAN binding protein 2: 0.4987: 45: SNRNP200: Small nuclear ribonucleoprotein U5 subunit 200: 0.4809: 45: PSME4: Proteasome activator subunit 4: 0.4785: 45: VPS13C: Vacuolar protein sorting 13 homolog C: 0.4776: 45: ZNF638: " - Birc6 protein folding

Birc6 protein folding

WebBIRC6. Status. UniProtKB reviewed (Swiss-Prot) Organism. Homo sapiens (Human) Amino acids. 4857. Protein existence. Evidence at protein level. Annotation score. 5/5. Entry. … WebThus, the reciprocal inhibition between BIRC6 and caspase activation is a potential mecha-nism by which cells may coordinate survival and apoptotic processes [20,43,45,46]. BIRC6 has been shown to be important in cell cycle progression and DNA damage repair where it functions as a scaffold protein for assembly of the DNA damage repair machinery

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WebFeb 9, 2024 · BIRC6 adopts a dimeric, horseshoe-shaped architecture with a central cavity that allows for binding to target proteases. The pro-apoptotic protein SMAC binds very … WebHeat shock protein 47, also known as SERPINH1 is a serpin which serves as a human chaperone protein for collagen. Function. This protein is a member of the serpin superfamily of serine proteinase inhibitors. Its expression is induced by heat shock. HSP47 is expressed in the endoplasmic reticulum.

WebFeb 8, 2013 · Background BIRC6 is a member of the Inhibitors of Apoptosis Protein (IAP) family which is thought to protect a variety of cancer cells from apoptosis. The main objective of the present study was to investigate … WebBIRC6. TISSUE CELL TYPE TISSUES. ADIPOSE SUBCUTANEOUS ADIPOSE VISCERAL BREAST COLON HEART MUSCLE KIDNEY LIVER LUNG. PANCREAS PROSTATE SKELETAL MUSCLE SKIN STOMACH TESTIS THYROID. Cell type enrichment. ... The Human Protein Atlas project is funded by the Knut & Alice Wallenberg Foundation. ...

Webralph lauren mens shoes sale; harmony collection clothing; MON-SAT 10:00AM - 7:00PM PST WebPrefoldin (GimC) is a superfamily of proteins used in protein folding complexes. It is classified as a heterohexameric molecular chaperone in both archaea and eukarya, …

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WebMar 31, 2016 · View Full Report Card. Fawn Creek Township is located in Kansas with a population of 1,618. Fawn Creek Township is in Montgomery County. Living in Fawn … iman\u0027s beauty supply rock hill scWebBirc6 Human gene description i. Baculoviral IAP repeat containing 6: Predicted location i Intracellular: Mouse gene: ENSMUSG00000024073 (version 103) Pig gene: ENSSSCG00000008513 (version 103) Antibodies in assay i. No antibodies in assay HUMAN PROTEIN ATLAS INFORMATION; Tissue specificity i. Low tissue specificity ... iman\u0027s children picturesWebMar 21, 2024 · Complete information for BIRC6-AS1 gene (RNA Gene), BIRC6 Antisense RNA 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium ... BIRC6 Antisense RNA 1 (Non-Protein Coding) (HGNC, NCBI Entrez Gene) NONHSAG027421.2 ; HSALNG0146433 ; BIRC6 … iman\u0027s daughters photosWebMar 21, 2024 · BIRC6 (Baculoviral IAP Repeat Containing 6) is a Protein Coding gene. Diseases associated with BIRC6 include Brain Cancer and Schizophrenia . Among its related pathways are Signaling by ALK in cancer and Disease . Gene Ontology (GO) … TP53 (Tumor Protein P53) is a Protein Coding gene. Diseases associated with … iman\u0027s brasserie bradfordWebElevated BIRC6 protein expression may serve as a predictive marker for chemoresistance of NSCLCs and a poor prognostic factor for NSCLC patients. … iman\u0027s hair storeWebThe gene view histogram is a graphical view of mutations across BIRC6. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left. iman\\u0027s father mohamed abdulmajidWebDec 2, 2024 · Inhibitors of apoptosis proteins (IAPs) have been associated with tumor development and progression by affecting apoptosis through cell death signaling pathways. To date, eight IAPs (BIRC1–8) have been identified in mammalian cells. However, the role of IAPs in non–small cell lung cancer (NSCLC) development and progression has not … list of healthcare provider