Sialyl lewis
WebJun 8, 2010 · For example, sialyl-Lewis x (sLe x) antigens are the ligands for selectins and are involved in the recruitment of leukocytes to lymphoid tissues and inflammation sites . Glycan structures depend on the cell type, developmental stage and cell differentiation, and are modified in many pathologic states including cancers. WebOct 9, 2001 · The interaction of sialyl Lewis x, Lewis x, and α-l-Fuc-(1→3)-β-d-GlcNAc with isolectin A from Lotus tetragonolobus (LTL-A), and with Aleuria aurantia agglutinin (AAA) was studied using NMR experiments and surface plasmon resonance. Both lectins are specific for fucose residues. From NMR experiments it was concluded that α-l-Fuc-(1→3) …
Sialyl lewis
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WebJul 1, 2024 · Sialyl-Lewis x (sLex, CD15s) is a tetra-saccharide on the surface of leukocytes required for E-selectin-mediated rolling, a prerequisite for leukocytes to migrate out of the blood vessels. Here we show using flow cytometry that sLex expression on basophils and mast cell progenitors depends on fucosyltransferase 6 (FUT6). Web14 T Loại Phạm vi Tác giả hình không gian Các phát hiện chính T PPP nghiên cứu tối thiểu hóa phạm vi cho việc ra quyết định để đảm bảo tính toàn vẹn của quy trình; giảm thiểu việc cung cấp bảo lãnh, ư[.] - 123doc - thư viện trực tuyến, download tài liệu, tải
WebSialyl-Lewis X. SLeX is a key recognition determinant for selectins that allow endothelial cells to recruit lymphocytes to roll on the endothelium prior to extravasation into tissues. … WebApr 8, 2013 · The antibody CD15s (Cat#551344) against carbohydrate antigen sialyl lewis x, gives very good signal strength with low back ground on Western blots. Usually carbohydrate antibodies tend to give lot of background especially if they are IgM isotype. This antibody also gave very good signals in flow cytometry and confocal with very low …
WebFor example, induction of sialyl Lewis expression in cancer of digestive organs is accompanied by increased ability of cancer cells to adhere to endothelial cells through endothelial E-selectin. 17 However, CA 19-9 is also secreted by normal biliary epithelium, and can be markedly elevated because of benign biliary stricture, extra-pancreatic ... WebGlobo-系列醣體被認為與癌症的演進有很高的關聯性。這些醣體之中，DSGb5被發現大量表達於腎細胞癌 (RCC) 且與 RCC 的轉移有關；而在乳癌細胞表面則大量表現 Gb5、SSEA4以及 Globo H。除外，唾液酸常被發現存在於細胞表面醣體的末端。唾液酸免疫球蛋白凝集素 (Siglecs) 藉由辨識病原體表面的唾液酸來調節 ...
WebSialyl Lewis x, Sodium Salt - CAS 98603-84-0 - Calbiochem Enzymatically prepared tetrasaccharide which acts as a minimal binding ligand for E-selectins. - Find MSDS or SDS, a COA, data sheets and more information.
WebJul 3, 2002 · A sialyl Lewis X (sLex) mimetic compound, 2-(trimethylsilyl)ethyl 3-O-carboxymethyl-β-d-galactopyranosyl-(1→4)-[α-l-fucosyl-(1→6)]-β-d-glucopyranoside (2a), … lake county superior court holidaysWebFeb 15, 2024 · The sialyl Lewis x (sLe x) reviewed in this paper is a derivative of the Lewis blood group antigen structure, also is a surface glycan. The monofucosyl substitution of the type 2 chain and α2,3-sialylation result in the formation of sLe x antigen [ 2 ]. helia round mirrored metal wall sculptureWebrate antigens, sialyl Lewisx (sLex) and sialyl Lewisa (sLea) are involved in colorectal cancer metastasis. METHODS: Metastatic abilities of human colon cancer cell variants that were selected for their high or low cell surface levels of sLex (KM12-HX and KM12-LX, respectively) were analyzed. Also, immunohistochemical expressions of sLex and sLea in … lake county supervisor moke simonSialyl Lewis (sLeX), also known as cluster of differentiation 15s (CD15s) or stage-specific embryonic antigen 1 (SSEA-1), is a tetrasaccharide carbohydrate which is usually attached to O-glycans on the surface of cells. It is known to play a vital role in cell-to-cell recognition processes. It is also the means by which … See more Sialyl-Lewis X is a tetrasaccharide composed of a sialic acid, fucose and an N-acetyllactosamine. Its systematic name is 5-acetylneuraminyl-(2-3)-galactosyl-(1-4)-(fucopyranosyl-(1-3))-N-acetylglucosamine (Neu5Acα2-3Galβ1 … See more Leukocyte homing Sialyl-Lewis is important in leukocyte tethering and rolling. Leukocytes move through the blood … See more The term Lewis in its name comes from the name of a family of people who suffered from a red blood cell incompatibility. The studies done on these individuals' red blood cells led to the discovery of sialyl Lewis X. Sialyl Lewis x is a very important … See more Leukocyte adhesion deficiency Defective synthesis of the sialyl Lewis antigen results in immunodeficiency (leukocyte adhesion deficiency type 2). Defective synthesis can be caused by the loss of fucosyltransferase, impairing the glycosylation of the … See more • CA19-9 (Sialyl-Lewis A) See more • Chen, G.-Y.; Osada, H.; Santamaria-Babi, L. F.; Kannagi, R. (7 November 2006). "Interaction of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytes" See more lake county superior court addressWebCD15s (sialyl Lewis x), a tetrasaccharide carbohydrate, is the α2-3 sialylated form of lacto-N-fucopentaose III (CD15) . In addition to eTreg cells and some memory and/or activated T cells, CD15s is highly expressed on … heliar siteWebG. Kretzschmar is an academic researcher. The author has contributed to research in topic(s): Sialyl-Lewis X & Oligosaccharide. The author has an hindex of 1, co-authored 3 publication(s) receiving 60 citation(s). heliar siaWebFeb 23, 2024 · Figure 1.Cell-surface fucosylated antigens. Type I (H1, Lewis a, Lewis b, and sialyl Lewis a) and type II (H2, Lewis x, Lewis y, and sialyl Lewis x) Lewis antigens are terminal fucosylated carbohydrate motifs decorating cell surface glycoproteins or glycolipids.In the case of glycoproteins, N- and O-linked glycans containing Lewis … lake county sun times