Small highly active dnas that hydrolyze dna
WebbThe development of a simple DNA sensor based on DNAzyme and PCR and aimed at the detection of low concentrations of zinc (II) ions, which showed sensitivity (10 nM) and high specificity for zinc ion detection is described. AbstractThe development of a simple sensor (9NL27-Zn) based on DNAzyme and PCR and aimed at the detection of low … Webb6 okt. 2024 · Herein, we propose a DNAzyme-guided DNA amplification motor through the facile built-in of a stimuli-responsive DNAzyme brake to facilitate the in vivo sensitive imaging of biomarkers by minimizing the off-site signal leakage in living systems.
Small highly active dnas that hydrolyze dna
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Webb14 okt. 2024 · DNA nanosponges are an emerging attractive type of nanocarriers for targeted therapeutics due to their ability to integrate diverse molecules, including DNA … Webb14 okt. 2024 · Catalytic DNAs, mainly DNA/RNA-cleaving DNAs, ... with the total 17 conserved nucleotides forming a catalytic loop to site-specifically hydrolyze DNA in the loop upon the supplementation of Zn 2+ ... Small, highly active DNAs that hydrolyze DNA. J. Am. Chem. Soc., 135 (2013), pp. 9121-9129.
Webbhydrolyzing DNAs is further highlighted by the fact that it has been relatively straightforward to create deoxyribozymes that promote DNA cleavage by oxidative 4 or … WebbDNA phosphoester bonds are exceedingly resistant to hydrolysis in the absence of chemical or enzymatic catalysts. This property is particularly important for organisms …
Webbför 2 dagar sedan · Herein, based on the mobility change of DNA in denaturing gels, we develop a selection strategy to discover a series of 40-45 nt small DNAs that can bind Zn2+ and Cd2+ specifically and... Webb7 dec. 2024 · DNA nanotechnology, in particular DNA origami, enables the bottom-up self-assembly of micrometre-scale, three-dimensional structures with nanometre-precise features 1,2,3,4,5,6,7,8,9,10,11,12 ...
WebbSmall, Highly Active DNAs That Hydrolyze DNA: 23679108: 10.1021/ja403585e: 2013: Liu, Y. He, J. Breaking the conservation of guanine residues in the catalytic loop of 10–23 DNAzyme by position-specific nucleobase modifications for rate enhancement: 23615852: 10.1039/c3cc42067a: 2024: Lee, Y. Silverman, S. K
crystal glass ornamentsWebb10 jan. 2024 · Developing nanomaterial-based enzyme mimics for DNA cleavage is an interesting challenge and it has many potential applications. Single-layered graphene … crystal glass oil candlesWebbMembers of the single-stranded DNA pool contain two 15 nt primer binding sites (5′ and 3′ termini) and two 50 nt random-sequence domains ... Reported in... Year of Publication … crystal glass ontarioWebbSmall, highly active DNAs that hydrolyze DNA. Article. Full-text available. May 2013; J AM CHEM SOC; Hongzhou Gu; Kazuhiro Furukawa; Zasha Weinberg; Daniel F Berenson; Ronald R Breaker; dwelling trailersWebbNatural DNA sequences conforming to the class I consensus sequence and structure were found that undergo hydrolysis under selection conditions (2 mM Zn 2+, pH 7), which … crystal glass omaha neWebbJournal of the American Chemical Society, 135 (24), 9121–9129 10.1021/ja403585e. Gu, H., Furukawa, K., Weinberg, Z., Berenson, D. F., & Breaker, R. R. (2013). Small, Highly … crystal glass owlWebb6 juni 2013 · The identification of small DNA-cleaving deoxyribozymes that function with high speed under mild reaction conditions should permit their use in various … dwelling tv show